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Antigenic Specificity | Alsin (ALS2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. |
Immunogen | KLH-conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2. |
Other Names | ALS2, ALS2CR6, ALSJ, IAHSP, Alsin, PLSJ, KIAA1563, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 protein, ALS2, ALS2, ALS2 , ALS2 , ALS2CR6, ALS2CR6, ALS2CR6 , ALS2CR6 , ALSJ, ALSJ, ALSJ , ALSJ , IAHSP, IAHSP, IAHSP , IAHSP , Alsin, Alsin, Alsin , Alsin , PLSJ, PLSJ, PLSJ , PLSJ , KIAA1563, KIAA1563, KIAA1563 , KIAA1563 , Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein , Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein , Amyotrophic lateral sclerosis 2 protein, Amyotrophic lateral sclerosis 2 protein, Amyotrophic lateral sclerosis 2 protein , Amyotrophic lateral sclerosis 2 protein |
Gene, Accession # | UniProt: Q96Q42 |
Catalog # | abx032830 |
Price | please inquire |
Order / More Info | Alsin (ALS2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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