Edit |   |
---|---|
Antigenic Specificity | Tryptase Delta (TPSD1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. |
Immunogen | KLH-conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human TPSD1. |
Other Names | TPSD1, Tryptase delta, Delta-tryptase, HmMCP-3-like tryptase III, Mast cell mMCP-7-like, Tryptase-3, TPSD1, TPSD1, TPSD1 , TPSD1 , Tryptase delta, Tryptase delta, Tryptase delta , Tryptase delta , Delta-tryptase, Delta-tryptase, Delta-tryptase , Delta-tryptase , HmMCP-3-like tryptase III, HmMCP-3-like tryptase III, HmMCP-3-like tryptase III , HmMCP-3-like tryptase III , Mast cell mMCP-7-like, Mast cell mMCP-7-like, Mast cell mMCP-7-like , Mast cell mMCP-7-like , Tryptase-3, Tryptase-3, Tryptase-3 , Tryptase-3 |
Gene, Accession # | TPSD1, UniProt: Q9BZJ3 |
Catalog # | abx025745 |
Price | please inquire |
Order / More Info | Tryptase Delta (TPSD1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950