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Antigenic Specificity | MEK Kinase Kinase 4 (MAP4K4) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing. |
Immunogen | Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli. |
Other Names | HGK, NIK, MEKKK4, FLH21957, MAP4K4, FLJ10410, FLJ20373, FLJ90111, KIAA0687, HPK/GCK-like kinase HGK, M4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck interacting kinase, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, mitogen-activated protein kinase kinase kinase kinase 4, HGK, HGK, HGK , HGK , NIK, NIK, NIK , NIK , MEKKK4, MEKKK4, MEKKK4 , MEKKK4 , FLH21957, FLH21957, FLH21957 , FLH21957 , MAP4K4, MAP4K4, MAP4K4 , MAP4K4 , FLJ10410, FLJ10410, FLJ10410 , FLJ10410 , FLJ20373, FLJ20373, FLJ20373 , FLJ20373 , FLJ90111, FLJ90111, FLJ90111 , FLJ90111 , KIAA0687, KIAA0687, KIAA0687 , KIAA0687 , HPK/GCK-like kinase HGK, HPK/GCK-like kinase HGK, HPK/GCK-like kinase HGK , HPK/GCK-like kinase HGK , M4K4, M4K4, M4K4 , M4K4 , MAPK/ERK kinase kinase kinase 4, MAPK/ERK kinase kinase kinase 4, MAPK/ERK kinase kinase kinase 4 , MAPK/ERK kinase kinase kinase 4 , MEK kinase kinase 4, MEK kinase kinase 4, MEK kinase kinase 4 , MEK kinase kinase |
Gene, Accession # | MAP4K4, Gene ID: 9448, UniProt: O95819 |
Catalog # | abx010331 |
Price | please inquire |
Order / More Info | MEK Kinase Kinase 4 (MAP4K4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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