Edit |   |
---|---|
Antigenic Specificity | BAG Family Molecular Chaperone Regulator 4 (BAG4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. |
Immunogen | KLH-conjugated synthetic peptide between 381-409 amino acids from the C-terminal region of human BAG4. |
Other Names | BAG4, BAG-4, BAG Family Molecular Chaperone Regulator 4, BCL2 Associated Athanogene 4, SODD, Silencer Of Death Domains, BAG Cochaperone 4, BAG4, BAG4, BAG4 , BAG4 , BAG-4, BAG-4, BAG-4 , BAG-4 , BAG Family Molecular Chaperone Regulator 4, BAG Family Molecular Chaperone Regulator 4, BAG Family Molecular Chaperone Regulator 4 , BAG Family Molecular Chaperone Regulator 4 , BCL2 Associated Athanogene 4, BCL2 Associated Athanogene 4, BCL2 Associated Athanogene 4 , BCL2 Associated Athanogene 4 , SODD, SODD, SODD , SODD , Silencer Of Death Domains, Silencer Of Death Domains, Silencer Of Death Domains , Silencer Of Death Domains , BAG Cochaperone 4, BAG Cochaperone 4, BAG Cochaperone 4 , BAG Cochaperone 4 |
Gene, Accession # | BAG4, Gene ID: 9530, UniProt: O95429 |
Catalog # | abx028746 |
Price | please inquire |
Order / More Info | BAG Family Molecular Chaperone Regulator 4 (BAG4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950