CD79B(CD79b, B29, IGB, Ig-beta) (Polatuzumab biosimilar) Antibody from ABBEXA LTD

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Antigenic SpecificityCD79B(CD79b, B29, IGB, Ig-beta) (Polatuzumab biosimilar)
Clonemonoclonal
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1 kappa
FormatProtein A/G purified
Size100 µg, 1 mg,
Concentrationtypically between 0.5-2.0 mg/ml.
ApplicationsELISA, WB
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DescriptionPolatuzumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting CD79B(CD79b, B29, IGB, Ig-beta), for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications.

B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain. CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR). CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
Immunogenn/a
Other NamesPolatuzumab, CD79B(CD79b, B29, IGB, Ig-beta)
Gene, Accession #n/a
Catalog #abx831275
Priceplease inquire
Order / More InfoCD79B(CD79b, B29, IGB, Ig-beta) (Polatuzumab biosimilar) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

Customer Service: info@abbexa.com
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U.S. Office
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Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413

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Telephone: +44 (0) 1223 755950


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