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Antigenic Specificity | 26S Proteasome Regulatory Subunit 6B (PSMC4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 20 µg, 50 µg, 100 µg, 200 µg+ |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 26S Proteasome Regulatory Subunit 6B (PSMC4) antibody is a Rabbit polyclonal against 26S Proteasome Regulatory Subunit 6B (PSMC4). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Recombinant Human 26S protease regulatory subunit 6B protein (112-181AA). |
Other Names | 26S protease regulatory subunit 6B, 26S proteasome AAA-ATPase subunit RPT3, MB67-interacting protein, MIP224, Proteasome 26S subunit ATPase 4, Tat-binding protein 7, TBP-7, PSMC4, TBP7, proteasome (prosome, macropain) 26S subunit, ATPase, 4, MGC13687, MGC23214, MGC8570, S6, RPT3, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 6B , 26S protease regulatory subunit 6B , 26S proteasome AAA-ATPase subunit RPT3, 26S proteasome AAA-ATPase subunit RPT3, 26S proteasome AAA-ATPase subunit RPT3 , 26S proteasome AAA-ATPase subunit RPT3 , MB67-interacting protein, MB67-interacting protein, MB67-interacting protein , MB67-interacting protein , MIP224, MIP224, MIP224 , MIP224 , Proteasome 26S subunit ATPase 4, Proteasome 26S subunit ATPase 4, Proteasome 26S subunit ATPase 4 , Proteasome 26S subunit ATPase 4 , Tat-binding protein 7, Tat-binding protein 7, Tat-binding protein 7 , Tat-binding protein 7 , TBP-7, TBP-7, TBP-7 , TBP-7 , PSMC4, |
Gene, Accession # | PSMC4, Gene ID: 5704, NCBI: NP_006494.1, NM_006503.3, NP_694546.1, NM_153001.2, UniProt: P43686 |
Catalog # | abx318162 |
Price | please inquire |
Order / More Info | 26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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