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Antigenic Specificity | Macrophage Mannose Receptor 1 (MRC1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Macrophage Mannose Receptor 1 (MRC1) antibody is a Rabbit polyclonal antibody for the detection of CD206. CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia. |
Immunogen | mannose receptor, C type 1 |
Other Names | Macrophage mannose receptor 1, MMR, CD206 antigen, MRC1, CLEC13D, CLEC13DL, MRC1L1, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Human mannose receptor, hMR, Macrophage mannose receptor 1-like protein 1, CD206, Macrophage mannose receptor 1, Macrophage mannose receptor 1, Macrophage mannose receptor 1 , Macrophage mannose receptor 1 , MMR, MMR, MMR , MMR , CD206 antigen, CD206 antigen, CD206 antigen , CD206 antigen , MRC1, MRC1, MRC1 , MRC1 , CLEC13D, CLEC13D, CLEC13D , CLEC13D , CLEC13DL, CLEC13DL, CLEC13DL , CLEC13DL , MRC1L1, MRC1L1, MRC1L1 , MRC1L1 , C-type lectin domain family 13 member D, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D , C-type lectin domain family 13 member D , C-type lectin domain family 13 member D-like, C-type lectin domain family 13 member D-like, C-type lectin domain family 13 member D-like , C-type lectin domain family 13 member D-like , Human mannose receptor, Human manno |
Gene, Accession # | MRC1, Gene ID: 4360, UniProt: P22897 |
Catalog # | abx216643 |
Price | please inquire |
Order / More Info | Macrophage Mannose Receptor 1 (MRC1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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