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Antigenic Specificity | Chemokine C-C-Motif Receptor 10 (CCR10) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833) ; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]). |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR10. |
Other Names | C-C chemokine receptor type 10, C-C CKR-10, CC-CKR-10, CCR-10, G-protein coupled receptor 2, CCR10, GPR2, CC chemokine receptor 10, G protein-coupled receptor 2, C-C chemokine receptor type 10, C-C chemokine receptor type 10, C-C chemokine receptor type 10 , C-C chemokine receptor type 10 , C-C CKR-10, C-C CKR-10, C-C CKR-10 , C-C CKR-10 , CC-CKR-10, CC-CKR-10, CC-CKR-10 , CC-CKR-10 , CCR-10, CCR-10, CCR-10 , CCR-10 , G-protein coupled receptor 2, G-protein coupled receptor 2, G-protein coupled receptor 2 , G-protein coupled receptor 2 , CCR10, CCR10, CCR10 , CCR10 , GPR2, GPR2, GPR2 , GPR2 , CC chemokine receptor 10, CC chemokine receptor 10, CC chemokine receptor 10 , CC chemokine receptor 10 , G protein-coupled receptor 2, G protein-coupled receptor 2, G protein-coupled receptor 2 , G protein-coupled receptor 2 |
Gene, Accession # | UniProt: P46092 |
Catalog # | abx027576 |
Price | please inquire |
Order / More Info | Chemokine C-C-Motif Receptor 10 (CCR10) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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