Serine/Threonine-Protein Kinase 39 (SPAK) Antibody from ABBEXA LTD
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| Antigenic Specificity | Serine/Threonine-Protein Kinase 39 (SPAK) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas. SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SPAK. SPAK activates the p38 MAP kinase pathway in cotransfection assays. Full-length SPAK is expressed in the cytoplasm in transfected cells, while a mutant corresponding to caspase-cleaved STK39 localizes predominantly in the nucleus. |
| Immunogen | KLH-conjugated synthetic peptide between 346-376 amino acids from the Central region of human SPAK. |
| Other Names | SPAK, STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK, SPAK, SPAK , SPAK , STE20/SPS1-related proline-alanine-rich protein kinase, STE20/SPS1-related proline-alanine-rich protein kinase, STE20/SPS1-related proline-alanine-rich protein kinase , STE20/SPS1-related proline-alanine-rich protein kinase , Ste-20-related kinase, Ste-20-related kinase, Ste-20-related kinase , Ste-20-related kinase , DCHT, DCHT, DCHT , DCHT , Serine/threonine-protein kinase 39, Serine/threonine-protein kinase 39, Serine/threonine-protein kinase 39 , Serine/threonine-protein kinase 39 , STK39, STK39, STK39 , STK39 |
| Gene, Accession # | NCBI: NP_037365.2, UniProt: Q9UEW8 |
| Catalog # | abx033798 |
| Price | please inquire |
| Order / More Info | Serine/Threonine-Protein Kinase 39 (SPAK) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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