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Antigenic Specificity | Carnitine O-Palmitoyltransferase 1, Brain Isoform (CPT1C) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine. |
Immunogen | KLH-conjugated synthetic peptide between 596-625 amino acids from the C-terminal region of human CPT1C. |
Other Names | Carnitine O-palmitoyltransferase 1, brain isoform, CPT1-B, CPT IC, Carnitine O-palmitoyltransferase I, CPTI-B, Carnitine palmitoyltransferase 1C, CPT1C, CATL1, CPT1P, CPTIC, FLJ23809, CPT1-like pseudogene, carnitine acyltransferase-like protein 1, carnitine palmitoyltransferase I related C, Carnitine O-palmitoyltransferase 1, Carnitine O-palmitoyltransferase 1, Carnitine O-palmitoyltransferase 1 , Carnitine O-palmitoyltransferase 1 , brain isoform, brain isoform, brain isoform , brain isoform , CPT1-B, CPT1-B, CPT1-B , CPT1-B , CPT IC, CPT IC, CPT IC , CPT IC , Carnitine O-palmitoyltransferase I, Carnitine O-palmitoyltransferase I, Carnitine O-palmitoyltransferase I , Carnitine O-palmitoyltransferase I , CPTI-B, CPTI-B, CPTI-B , CPTI-B , Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase 1C , Carnitine palmitoyltransferase 1C , CPT1C, CPT1C, CPT1C , CPT1C , CATL1, CATL1, CATL1 , CATL1 , CPT1P, CPT1P, CPT1P , CPT1P , CPTIC, CP |
Gene, Accession # | CPT1C, UniProt: Q8TCG5 |
Catalog # | abx028655 |
Price | please inquire |
Order / More Info | Carnitine O-Palmitoyltransferase 1, Brain Isoform (CPT1C) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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