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Antigenic Specificity | TSC2 (pS1798) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, IF/ICC, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1798 of human TSC2. |
Other Names | TSC2, LAM, Tuberous sclerosis 2 protein, Tuberous sclerosis 2, TSC4, Tuberin, TSC2, TSC2, TSC2 , TSC2 , LAM, LAM, LAM , LAM , Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein , Tuberous sclerosis 2 protein , Tuberous sclerosis 2, Tuberous sclerosis 2, Tuberous sclerosis 2 , Tuberous sclerosis 2 , TSC4, TSC4, TSC4 , TSC4 , Tuberin, Tuberin, Tuberin , Tuberin |
Gene, Accession # | UniProt: P49815 |
Catalog # | abx032001 |
Price | please inquire |
Order / More Info | TSC2 (pS1798) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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