Metabotropic Glutamate Receptor 5 (GRM5) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Metabotropic Glutamate Receptor 5 (GRM5) antibody, protein, ELISA kits.
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| Antigenic Specificity | Metabotropic Glutamate Receptor 5 (GRM5) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 (also known as GPRC1E) and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM5 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. |
| Immunogen | KLH-conjugated synthetic peptide between 1020-1050 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 5 (GPRC1E). |
| Other Names | GRM5, GPRC1E, MGLUR5, Metabotropic glutamate receptor 5, GRM5, GRM5, GRM5 , GRM5 , GPRC1E, GPRC1E, GPRC1E , GPRC1E , MGLUR5, MGLUR5, MGLUR5 , MGLUR5 , Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 5 , Metabotropic glutamate receptor 5 |
| Gene, Accession # | UniProt: P41594 |
| Catalog # | abx032808 |
| Price | please inquire |
| Order / More Info | Metabotropic Glutamate Receptor 5 (GRM5) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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