Edit |   |
---|---|
Antigenic Specificity | Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Factor (LITAF) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LITAF antibody is a Rabbit polyclonal antibody against LITAF. Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. |
Immunogen | Recombinant protein of human LITAF. |
Other Names | Lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, Small integral membrane protein of lysosome/late endosome, p53-induced gene 7 protein, LITAF, PIG7, SIMPLE, lipopolysaccharide-induced TNF factor, CMT1C, FLJ38636, MGC116698, MGC116700, MGC116701, MGC125274, MGC125275, MGC125276, TP53I7, tumor protein, Lipopolysaccharide-induced tumor necrosis factor-alpha factor, Lipopolysaccharide-induced tumor necrosis factor-alpha factor, Lipopolysaccharide-induced tumor necrosis factor-alpha factor , Lipopolysaccharide-induced tumor necrosis factor-alpha factor , LPS-induced TNF-alpha factor, LPS-induced TNF-alpha factor, LPS-induced TNF-alpha factor , LPS-induced TNF-alpha factor , Small integral membrane protein of lysosome/late endosome, Small integral membrane protein of lysosome/late endosome, Small integral membrane protein of lysosome/late endosome , Small integral membrane protein of lysosome/late endosome , p53-induced gene 7 protein, p53-indu |
Gene, Accession # | LITAF, Gene ID: 9516, UniProt: Q99732 |
Catalog # | abx004189 |
Price | please inquire |
Order / More Info | Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Factor (LITAF) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950