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Antigenic Specificity | Thioredoxin (TXN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). |
Immunogen | KLH-conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN. |
Other Names | TXN, ADF, ATL-derived factor, SASP, Thioredoxin, TRX1, Thioredoxin delta 3, TRX, TXN delta 3, TRDX, DKFZp686B1993, MGC61975, TXN, TXN, TXN , TXN , ADF, ADF, ADF , ADF , ATL-derived factor, ATL-derived factor, ATL-derived factor , ATL-derived factor , SASP, SASP, SASP , SASP , Thioredoxin, Thioredoxin, Thioredoxin , Thioredoxin , TRX1, TRX1, TRX1 , TRX1 , Thioredoxin delta 3, Thioredoxin delta 3, Thioredoxin delta 3 , Thioredoxin delta 3 , TRX, TRX, TRX , TRX , TXN delta 3, TXN delta 3, TXN delta 3 , TXN delta 3 , TRDX, TRDX, TRDX , TRDX , DKFZp686B1993, DKFZp686B1993, DKFZp686B1993 , DKFZp686B1993 , MGC61975, MGC61975, MGC61975 , MGC61975 |
Gene, Accession # | NCBI: NP_001231867.1, NP_003320.2, UniProt: P10599 |
Catalog # | abx034701 |
Price | please inquire |
Order / More Info | Thioredoxin (TXN) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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