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Antigenic Specificity | Paired Box Protein Pax-8 (PAX8) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PAX8 antibody is a Rabbit polyclonal antibody against PAX8. PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX8 has 5 isoforms with calculated MW 31kd, 34kd, 41kd, 43kd and 48kd. And there is a 60kd band corresponding to the electrophoretic mobility of PAX8 (PMID:15650356). Proteintech's 10336-1-AP antibody has cross-reactivities with the other PAX family members. |
Immunogen | Recombinant protein of human PAX8. |
Other Names | OTTHUMP00000158659, OTTHUMP00000158660, OTTHUMP00000203723, OTTHUMP00000203724, Paired box 8, Paired box gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired box protein Pax-8, Paired domain gene 8, PAX 8, PAX8, HGNC:8622, OTTHUMP00000158659, OTTHUMP00000158659, OTTHUMP00000158659 , OTTHUMP00000158659 , OTTHUMP00000158660, OTTHUMP00000158660, OTTHUMP00000158660 , OTTHUMP00000158660 , OTTHUMP00000203723, OTTHUMP00000203723, OTTHUMP00000203723 , OTTHUMP00000203723 , OTTHUMP00000203724, OTTHUMP00000203724, OTTHUMP00000203724 , OTTHUMP00000203724 , Paired box 8, Paired box 8, Paired box 8 , Paired box 8 , Paired box gene 8, Paired box gene 8, Paired box gene 8 , Paired box gene 8 , paired box homeotic gene 8, paired box homeotic gene 8, paired box homeotic gene 8 , paired box homeotic gene 8 , Paired box protein Pax 8, Paired box protein Pax 8, Paired box protein Pax 8 , Paired box protein Pax 8 , Paired box protein Pax-8, Paired box protein Pax-8, Paired box prote |
Gene, Accession # | PAX8, Gene ID: 7849, UniProt: Q06710 |
Catalog # | abx000957 |
Price | please inquire |
Order / More Info | Paired Box Protein Pax-8 (PAX8) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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