Paired Box Protein Pax-8 (PAX8) Antibody from ABBEXA LTD

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Antigenic SpecificityPaired Box Protein Pax-8 (PAX8)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IF/ICC
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DescriptionPAX8 antibody is a Rabbit polyclonal antibody against PAX8. PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX8 has 5 isoforms with calculated MW 31kd, 34kd, 41kd, 43kd and 48kd. And there is a 60kd band corresponding to the electrophoretic mobility of PAX8 (PMID:15650356). Proteintech's 10336-1-AP antibody has cross-reactivities with the other PAX family members.
ImmunogenRecombinant protein of human PAX8.
Other NamesOTTHUMP00000158659, OTTHUMP00000158660, OTTHUMP00000203723, OTTHUMP00000203724, Paired box 8, Paired box gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired box protein Pax-8, Paired domain gene 8, PAX 8, PAX8, HGNC:8622, OTTHUMP00000158659, OTTHUMP00000158659, OTTHUMP00000158659 , OTTHUMP00000158659 , OTTHUMP00000158660, OTTHUMP00000158660, OTTHUMP00000158660 , OTTHUMP00000158660 , OTTHUMP00000203723, OTTHUMP00000203723, OTTHUMP00000203723 , OTTHUMP00000203723 , OTTHUMP00000203724, OTTHUMP00000203724, OTTHUMP00000203724 , OTTHUMP00000203724 , Paired box 8, Paired box 8, Paired box 8 , Paired box 8 , Paired box gene 8, Paired box gene 8, Paired box gene 8 , Paired box gene 8 , paired box homeotic gene 8, paired box homeotic gene 8, paired box homeotic gene 8 , paired box homeotic gene 8 , Paired box protein Pax 8, Paired box protein Pax 8, Paired box protein Pax 8 , Paired box protein Pax 8 , Paired box protein Pax-8, Paired box protein Pax-8, Paired box prote
Gene, Accession #PAX8, Gene ID: 7849, UniProt: Q06710
Catalog #abx000957
Priceplease inquire
Order / More InfoPaired Box Protein Pax-8 (PAX8) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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