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Antigenic Specificity | Protein Inhibitor of Activated STAT3 (PIAS3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PIAS3 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription) ] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier) E3 ligase stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor, catalyzing the covalent attachment of a SUMO protein to specific target substrates. PIAS3 plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. |
Immunogen | KLH-conjugated synthetic peptide between 588-619 amino acids of human PIAS3. |
Other Names | E3 SUMO-protein ligase PIAS3, FLJ14651, PIAS3, Protein inhibitor of activated STAT protein 3, protein inhibitor of activated STAT, 3, zinc finger, MIZ-type containing 5, ZMIZ5, PROTEIN INHIBITOR OF ACTIVATED STAT3, protein inhibitor of activated STAT 3, E3 SUMO-protein ligase PIAS3, E3 SUMO-protein ligase PIAS3, E3 SUMO-protein ligase PIAS3 , E3 SUMO-protein ligase PIAS3 , FLJ14651, FLJ14651, FLJ14651 , FLJ14651 , PIAS3, PIAS3, PIAS3 , PIAS3 , Protein inhibitor of activated STAT protein 3, Protein inhibitor of activated STAT protein 3, Protein inhibitor of activated STAT protein 3 , Protein inhibitor of activated STAT protein 3 , protein inhibitor of activated STAT, protein inhibitor of activated STAT, protein inhibitor of activated STAT , protein inhibitor of activated STAT , 3, 3, 3 , 3 , zinc finger, zinc finger, zinc finger , zinc finger , MIZ-type containing 5, MIZ-type containing 5, MIZ-type containing 5 , MIZ-type containing 5 , ZMIZ5, ZMIZ5, ZMIZ5 , ZMIZ5 , PROTEIN INH |
Gene, Accession # | NCBI: NP_006090.2, UniProt: Q9Y6X2 |
Catalog # | abx026820 |
Price | please inquire |
Order / More Info | Protein Inhibitor of Activated STAT3 (PIAS3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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