Poly(RC) Binding Protein 2 (PCBP2) Antibody from ABBEXA LTD

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Antigenic SpecificityPoly(RC) Binding Protein 2 (PCBP2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IHC, IF/ICC
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DescriptionPCBP2 antibody is a Rabbit polyclonal antibody against PCBP2. The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
ImmunogenRecombinant protein of human PCBP2.
Other NamesHNRPE2, MGC110998, hnRNP-E2, PCBP2, HNRPE2, HNRPE2, HNRPE2 , HNRPE2 , MGC110998, MGC110998, MGC110998 , MGC110998 , hnRNP-E2, hnRNP-E2, hnRNP-E2 , hnRNP-E2 , PCBP2, PCBP2, PCBP2 , PCBP2
Gene, Accession #PCBP2, Gene ID: 5094, UniProt: Q15366
Catalog #abx001971
Priceplease inquire
Order / More InfoPoly(RC) Binding Protein 2 (PCBP2) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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