Insulin Degrading Enzyme (IDE) Antibody from ABBEXA LTD
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| Antigenic Specificity | Insulin Degrading Enzyme (IDE) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IDE antibody is a Rabbit polyclonal antibody against IDE. This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009]. |
| Immunogen | Recombinant protein of human IDE. |
| Other Names | FLJ35968, INSULYSIN, IDE, insulin-degrading enzyme, 1300012G03Rik, 4833415K22Rik, AA675336, AI507533, insulinase, Abeta-degrading protease, Insulin protease, FLJ35968, FLJ35968, FLJ35968 , FLJ35968 , INSULYSIN, INSULYSIN, INSULYSIN , INSULYSIN , IDE, IDE, IDE , IDE , insulin-degrading enzyme, insulin-degrading enzyme, insulin-degrading enzyme , insulin-degrading enzyme , 1300012G03Rik, 1300012G03Rik, 1300012G03Rik , 1300012G03Rik , 4833415K22Rik, 4833415K22Rik, 4833415K22Rik , 4833415K22Rik , AA675336, AA675336, AA675336 , AA675336 , AI507533, AI507533, AI507533 , AI507533 , insulinase, insulinase, insulinase , insulinase , Abeta-degrading protease, Abeta-degrading protease, Abeta-degrading protease , Abeta-degrading protease , Insulin protease, Insulin protease, Insulin protease , Insulin protease |
| Gene, Accession # | IDE, Gene ID: 3416, UniProt: P14735 |
| Catalog # | abx001373 |
| Price | please inquire |
| Order / More Info | Insulin Degrading Enzyme (IDE) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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