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Antigenic Specificity | Signal Transducer and Activator of Transcription 3 Phospho-Tyr705 (STAT3 pY705) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Stat3 (pY705) Antibody is a Rabbit Polyclonal antibody against Stat3 (pY705). The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Tyr705 of human Stat3. |
Other Names | Signal transducer and activator of transcription 3, STAT3, APRF, DNA-Binding Protein APRF, ADMIO, HIES, Acute-Phase Response Factor, FLJ20882, MGC16063, Signal transducer and activator of transcription 3, STAT3, APRF, DNA-Binding Protein APRF, ADMIO, HIES, Acute-Phase Response Factor, signal transducer and activator of transcription 3 (acute-phase response factor), Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, STAT3, STAT3, STAT3, STAT3, APRF, APRF, APRF, APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF, ADMIO, ADMIO, ADMIO, ADMIO, HIES, HIES, HIES, HIES, Acute-Phase Response Factor, Acute-Phase Response Factor, Acute-Phase Response Factor, Acute-Phase Response Factor, FLJ20882, FLJ20882, FLJ20882, FLJ20882, MGC16063, MGC16063, MGC16063, MGC16063, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 3, STAT3, STAT3, STAT3, STAT3, APRF, APRF, APRF, APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF, DNA-Binding Protein APRF, ADMIO, ADMIO, ADMIO, ADMIO, HIES, HIES, HIES, HIES, Acute-Phase Response Factor, Acute-Phase Response Factor, Acute-Phase Response Factor, Acute-Phase Response Factor, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer and activator of transcription 3 (acute-phase response factor) |
Gene, Accession # | STAT3, Gene ID: 6774, UniProt: P40763 |
Catalog # | abx000144 |
Price | please inquire |
Order / More Info | Signal Transducer and Activator of Transcription 3 Phospho-Tyr705 (STAT3 pY705) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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