Tyrosine Kinase 2 (Tyk2) Antibody from ABBEXA LTD
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| Antigenic Specificity | Tyrosine Kinase 2 (Tyk2) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Tyk2 (tyrosine kinase 2),with 1187-amino acid protein (about 131kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN alpha, IFN beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance. |
| Immunogen | Purified recombinant fragment of Tyk2 expressed in E. Coli. |
| Other Names | JTK 1, JTK1, Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase TYK2, Non-receptor tyrosine-protein kinase TYK2, OTTHUMP00000232745, OTTHUMP00000232746, OTTHUMP00000232748, Protein Tyrosine Kinase 2, TYK 2, Tyk2, Tyrosine kinase 2, JTK 1, JTK 1, JTK 1 , JTK 1 , JTK1, JTK1, JTK1 , JTK1 , Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase 2 , Non receptor tyrosine protein kinase 2 , Non receptor tyrosine protein kinase TYK2, Non receptor tyrosine protein kinase TYK2, Non receptor tyrosine protein kinase TYK2 , Non receptor tyrosine protein kinase TYK2 , Non-receptor tyrosine-protein kinase TYK2, Non-receptor tyrosine-protein kinase TYK2, Non-receptor tyrosine-protein kinase TYK2 , Non-receptor tyrosine-protein kinase TYK2 , OTTHUMP00000232745, OTTHUMP00000232745, OTTHUMP00000232745 , OTTHUMP00000232745 , OTTHUMP00000232746, OTTHUMP00000232746, OTTHUMP00000232746 , OTTHUMP00000232746 , OTTHU |
| Gene, Accession # | TYK2, Gene ID: 7297, UniProt: P29597 |
| Catalog # | abx012306 |
| Price | please inquire |
| Order / More Info | Tyrosine Kinase 2 (Tyk2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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