PIK3R1/2/3 (pY467) Antibody from ABBEXA LTD

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Antigenic SpecificityPIK3R1/2/3 (pY467)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size50 µl, 100 µl, 200 µl,
Concentration> 1 mg/ml
ApplicationsWB
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DescriptionPIK3R1/2/3 (pY467) antibody is a Rabbit polyclonal antibody against PIK3R1/2/3 (pY467). Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
ImmunogenSynthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3.
Other Namesp85, GRB1, p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, PIK3R1, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), p85, p85 , p85 , p85, GRB1, GRB1 , GRB1 , GRB1, p85-ALPHA, p85-ALPHA , p85-ALPHA , p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha , Phosphatidylinositol 3-kinase regulatory subunit alpha , Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha , PI3-kinase regulatory subunit alpha , PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PI3K regulatory subunit alpha , PI3K regulatory subunit alpha , PI3K regulatory subunit alpha, PtdIns
Gene, Accession #PIK3R1, PIK3R2, PIK3R3, Gene ID: 5295/ 8503/ 5296, UniProt: P27986, Q92569, O00459
Catalog #abx000474
Priceplease inquire
Order / More InfoPIK3R1/2/3 (pY467) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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