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Antigenic Specificity | PIK3R1/2/3 (pY467) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl, |
Concentration | > 1 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PIK3R1/2/3 (pY467) antibody is a Rabbit polyclonal antibody against PIK3R1/2/3 (pY467). Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3. |
Other Names | p85, GRB1, p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, PIK3R1, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), p85, p85 , p85 , p85, GRB1, GRB1 , GRB1 , GRB1, p85-ALPHA, p85-ALPHA , p85-ALPHA , p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha , Phosphatidylinositol 3-kinase regulatory subunit alpha , Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha , PI3-kinase regulatory subunit alpha , PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PI3K regulatory subunit alpha , PI3K regulatory subunit alpha , PI3K regulatory subunit alpha, PtdIns |
Gene, Accession # | PIK3R1, PIK3R2, PIK3R3, Gene ID: 5295/ 8503/ 5296, UniProt: P27986, Q92569, O00459 |
Catalog # | abx000474 |
Price | please inquire |
Order / More Info | PIK3R1/2/3 (pY467) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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