Caspase 12 (CASP12) Antibody from ABBEXA LTD
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| Antigenic Specificity | Caspase 12 (CASP12) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. |
| Immunogen | KLH-conjugated synthetic peptide between 165-193 amino acids from the Central region of human CASP12. |
| Other Names | CASP-12, Casp12, Inactive caspase-12, CASP12P1, UNQ9415/PRO34398, CASP-12, CASP-12, CASP-12 , CASP-12 , Casp12, Casp12, Casp12 , Casp12 , Inactive caspase-12, Inactive caspase-12, Inactive caspase-12 , Inactive caspase-12 , CASP12P1, CASP12P1, CASP12P1 , CASP12P1 , UNQ9415/PRO34398, UNQ9415/PRO34398, UNQ9415/PRO34398 , UNQ9415/PRO34398 |
| Gene, Accession # | CASP12, UniProt: Q6UXS9 |
| Catalog # | abx026563 |
| Price | please inquire |
| Order / More Info | Caspase 12 (CASP12) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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