LIMK2 (pT505) Antibody from ABBEXA LTD
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| Antigenic Specificity | LIMK2 (pT505) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µl, 100 µl, 200 µl, |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LIMK2 (pT505) antibody is a Rabbit polyclonal antibody against LIMK2 (pT505). There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T505 of human LIMK2. |
| Other Names | kinase LIMK2, LIM domain kinase 2, LIMK-2, LIMK2, kinase LIMK2, kinase LIMK2, kinase LIMK2 , kinase LIMK2 , LIM domain kinase 2, LIM domain kinase 2, LIM domain kinase 2 , LIM domain kinase 2 , LIMK-2, LIMK-2, LIMK-2 , LIMK-2 , LIMK2, LIMK2, LIMK2 , LIMK2 |
| Gene, Accession # | LIMK2, Gene ID: 3985, UniProt: P53671 |
| Catalog # | abx000435 |
| Price | please inquire |
| Order / More Info | LIMK2 (pT505) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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