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Antigenic Specificity | POU Class 5 Homeobox 1 / OCT4 (POU5F1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factors containing the POU homeodomain have been shown to be important regulators of tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Two forms of OCT3 mRNA are expressed in adult tissues as a result of alternative splicing--OCT3A and OCT3B. Reverse transcriptase PCR showed low level of expression in both OCT3A and OCT3B mRNA in all adult human tissues examined. Oct3 is present in mouse oocytes before and after fertilization. When fertilized oocytes were injected with antisense Oct3 oligonucleotides or double-stranded DNA containing the octamer motif, embryonic DNA synthesis was inhibited and the embryos were arrested at the one-cell stage. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human OCT4 (OCT3). |
Other Names | POU5F1, POU Class 5 Homeobox 1, Octamer-Binding Transcription Factor 3, Octamer-Binding Protein 3, Octamer-Binding Protein 4, OTF-3, Oct-3, Oct-4, OTF3, OCT3, OCT4, POU-Type Homeodomain-Containing DNA-Binding Protein, POU Class 5 Homeobox 1 Transcript Variant OCT4B1, POU Class 5 Homeobox 1 Transcript Variant OCT4B2, POU Class 5 Homeobox 1 Transcript Variant OCT4B3, POU Class 5 Homeobox 1 Transcript Variant OCT4B4, POU Class 5 Homeobox 1 Transcript Variant OCT4B5, POU Class 5 Homeobox 1 Transcript Variant OCT4B6, POU Domain, Class 5, Transcription Factor 1, POU Domain Class 5, Transcription Factor 1, POU Domain Transcription Factor OCT4, POU ClassV Homeobox 1 Variant 2, OTF4, POU5F1, POU5F1, POU5F1 , POU5F1 , POU Class 5 Homeobox 1, POU Class 5 Homeobox 1, POU Class 5 Homeobox 1 , POU Class 5 Homeobox 1 , Octamer-Binding Transcription Factor 3, Octamer-Binding Transcription Factor 3, Octamer-Binding Transcription Factor 3 , Octamer-Binding Transcription Factor 3 , Octamer-Binding Pro |
Gene, Accession # | NCBI: NP_002692.2, UniProt: Q01860 |
Catalog # | abx031505 |
Price | please inquire |
Order / More Info | POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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