UDP-Glucose 4-Epimerase (GALE) Antibody from ABBEXA LTD

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Antigenic SpecificityUDP-Glucose 4-Epimerase (GALE)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB, IHC, IF/ICC
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DescriptionGALE antibody is a Rabbit polyclonal antibody against GALE. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
ImmunogenRecombinant protein of human GALE.
Other NamesGalactowaldenase, UDP-N-acetylgalactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-galactose 4-epimerase, GALE, SDR1E1, UDP-glucose 4-epimerase, Galactowaldenase, Galactowaldenase, Galactowaldenase , Galactowaldenase , UDP-N-acetylgalactosamine 4-epimerase, UDP-N-acetylgalactosamine 4-epimerase, UDP-N-acetylgalactosamine 4-epimerase , UDP-N-acetylgalactosamine 4-epimerase , UDP-GalNAc 4-epimerase, UDP-GalNAc 4-epimerase, UDP-GalNAc 4-epimerase , UDP-GalNAc 4-epimerase , UDP-N-acetylglucosamine 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-N-acetylglucosamine 4-epimerase , UDP-N-acetylglucosamine 4-epimerase , UDP-GlcNAc 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-GlcNAc 4-epimerase , UDP-GlcNAc 4-epimerase , UDP-galactose 4-epimerase, UDP-galactose 4-epimerase, UDP-galactose 4-epimerase , UDP-galactose 4-epimerase , GALE, GALE, GALE , GALE , SDR1E1, SDR1E1, SDR1E1 , SDR1E1 , UDP-glucose 4-epimerase, UDP-glucos
Gene, Accession #GALE, Gene ID: 2582, UniProt: Q14376
Catalog #abx005057
Priceplease inquire
Order / More InfoUDP-Glucose 4-Epimerase (GALE) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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