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Antigenic Specificity | UDP-Glucose 4-Epimerase (GALE) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GALE antibody is a Rabbit polyclonal antibody against GALE. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. |
Immunogen | Recombinant protein of human GALE. |
Other Names | Galactowaldenase, UDP-N-acetylgalactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-galactose 4-epimerase, GALE, SDR1E1, UDP-glucose 4-epimerase, Galactowaldenase, Galactowaldenase, Galactowaldenase , Galactowaldenase , UDP-N-acetylgalactosamine 4-epimerase, UDP-N-acetylgalactosamine 4-epimerase, UDP-N-acetylgalactosamine 4-epimerase , UDP-N-acetylgalactosamine 4-epimerase , UDP-GalNAc 4-epimerase, UDP-GalNAc 4-epimerase, UDP-GalNAc 4-epimerase , UDP-GalNAc 4-epimerase , UDP-N-acetylglucosamine 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-N-acetylglucosamine 4-epimerase , UDP-N-acetylglucosamine 4-epimerase , UDP-GlcNAc 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-GlcNAc 4-epimerase , UDP-GlcNAc 4-epimerase , UDP-galactose 4-epimerase, UDP-galactose 4-epimerase, UDP-galactose 4-epimerase , UDP-galactose 4-epimerase , GALE, GALE, GALE , GALE , SDR1E1, SDR1E1, SDR1E1 , SDR1E1 , UDP-glucose 4-epimerase, UDP-glucos |
Gene, Accession # | GALE, Gene ID: 2582, UniProt: Q14376 |
Catalog # | abx005057 |
Price | please inquire |
Order / More Info | UDP-Glucose 4-Epimerase (GALE) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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