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Antigenic Specificity | Signal Transducing Adaptor Molecule (STAM) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Stimulation of cells with cytokines initiates a signal transduction cascade involving cytokine receptors, Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). STAM for 'signal-transducing adaptor molecule, induced after stimulation of cells with cytokine IL2, is a component of signal transduction downstream of JAK3.1 Human STAM cDNA cloned from a T-cell cDNA library encodes a 540-amino acid protein precipitated by anti-phosphotyrosine. Northern blot analysis indicates that STAM is expressed as a 2.9-kb message in a wide variety of tissue and cell types. The STAM sequence contains a Src-homology 3 (SH3) domain and an immunoreceptor tyrosine-based activation motif (ITAM). It has been suggested that STAM acts as an adaptor molecule in signal transduction pathways from cytokine receptors. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human STAM. |
Other Names | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, STAM, DKFZp686J2352, STAM1, Signal transducing adapter molecule 1, STAM-1, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 , signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 , STAM, STAM, STAM , STAM , DKFZp686J2352, DKFZp686J2352, DKFZp686J2352 , DKFZp686J2352 , STAM1, STAM1, STAM1 , STAM1 , Signal transducing adapter molecule 1, Signal transducing adapter molecule 1, Signal transducing adapter molecule 1 , Signal transducing adapter molecule 1 , STAM-1, STAM-1, STAM-1 , STAM-1 |
Gene, Accession # | NCBI: NP_003464.1, UniProt: Q92783 |
Catalog # | abx031568 |
Price | please inquire |
Order / More Info | Signal Transducing Adaptor Molecule (STAM) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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