Signal Transducing Adaptor Molecule (STAM) Antibody from ABBEXA LTD

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Antigenic SpecificitySignal Transducing Adaptor Molecule (STAM)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionStimulation of cells with cytokines initiates a signal transduction cascade involving cytokine receptors, Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). STAM for 'signal-transducing adaptor molecule, induced after stimulation of cells with cytokine IL2, is a component of signal transduction downstream of JAK3.1 Human STAM cDNA cloned from a T-cell cDNA library encodes a 540-amino acid protein precipitated by anti-phosphotyrosine. Northern blot analysis indicates that STAM is expressed as a 2.9-kb message in a wide variety of tissue and cell types. The STAM sequence contains a Src-homology 3 (SH3) domain and an immunoreceptor tyrosine-based activation motif (ITAM). It has been suggested that STAM acts as an adaptor molecule in signal transduction pathways from cytokine receptors.
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human STAM.
Other Namessignal transducing adaptor molecule (SH3 domain and ITAM motif) 1, STAM, DKFZp686J2352, STAM1, Signal transducing adapter molecule 1, STAM-1, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 , signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 , STAM, STAM, STAM , STAM , DKFZp686J2352, DKFZp686J2352, DKFZp686J2352 , DKFZp686J2352 , STAM1, STAM1, STAM1 , STAM1 , Signal transducing adapter molecule 1, Signal transducing adapter molecule 1, Signal transducing adapter molecule 1 , Signal transducing adapter molecule 1 , STAM-1, STAM-1, STAM-1 , STAM-1
Gene, Accession #NCBI: NP_003464.1, UniProt: Q92783
Catalog #abx031568
Priceplease inquire
Order / More InfoSignal Transducing Adaptor Molecule (STAM) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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