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Antigenic Specificity | 26S Proteasome Non-ATPase Regulatory Subunit 1 (PSMD1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq]. |
Immunogen | KLH-conjugated synthetic peptide between 104-132 amino acids from the N-terminal region of human PSMD1. |
Other Names | PSMD1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit S1, 26S proteasome subunit p112, PSMD1, PSMD1, PSMD1 , PSMD1 , 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 1 , 26S proteasome non-ATPase regulatory subunit 1 , 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit RPN2 , 26S proteasome regulatory subunit RPN2 , 26S proteasome regulatory subunit S1, 26S proteasome regulatory subunit S1, 26S proteasome regulatory subunit S1 , 26S proteasome regulatory subunit S1 , 26S proteasome subunit p112, 26S proteasome subunit p112, 26S proteasome subunit p112 , 26S proteasome subunit p112 |
Gene, Accession # | PSMD1, Gene ID: 5707, UniProt: Q99460 |
Catalog # | abx028169 |
Price | please inquire |
Order / More Info | 26S Proteasome Non-ATPase Regulatory Subunit 1 (PSMD1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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