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Antigenic Specificity | Caspase 8 (CASP8) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg, |
Concentration | 2 mg/ml |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 8 (CASP8) antibody is a Rabbit polyclonal antibody for the detection of Caspase 8. Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3 (PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8. |
Immunogen | caspase 8, apoptosis-related cysteine peptidase |
Other Names | Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog, Fadd-Homologous Ice/Ced-3-Like Protease, Casp8, CASP-8, Caspase-8 subunit p18, Caspase-8 subunit p10, Caspase-8, Caspase 8, Cysteinyl Aspartate Specific Proteinases 8, Apoptotic cysteine protease, Apoptotic cysteine protease, Apoptotic cysteine protease , Apoptotic cysteine protease , Apoptotic protease Mch-5, Apoptotic protease Mch-5, Apoptotic protease Mch-5 , Apoptotic protease Mch-5 , CAP4, CAP4, CAP4 , CAP4 , Caspase-8 precursor, Caspase-8 precursor, Caspase-8 precursor , Caspase-8 precursor , FADD-homologous ICE/CED-3- like protease, FADD-homologous ICE/CED-3- like protease, FADD-homologous ICE/CED-3- like protease , FADD-homologous ICE/CED-3- like protease , FADD-like ICE, FADD-like ICE, FADD-like ICE , FADD-like ICE , FLICE, FLICE, FLICE , FLICE , |
Gene, Accession # | CASP8, Gene ID: 841, UniProt: Q14790 |
Catalog # | abx012069 |
Price | please inquire |
Order / More Info | Caspase 8 (CASP8) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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