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Antigenic Specificity | DNA-Dependent Protein Kinase Catalytic Subunit Phospho-Thr2609 (PRKDC pT2609) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, DB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Stem cell surface receptors and activate yeast MAPK pathway. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2609 of human DNA-PK. |
Other Names | PRKDC, Protein Kinase, DNA-Activated, Catalytic Subunit, DNA-Dependent Protein Kinase Catalytic Subunit, Protein Kinase, DNA-Activated, Catalytic Polypeptide, DNA-PK Catalytic Subunit, EC 2.7.11.1, DNA-PKcs, HYRC1, DNPK1, HYRC, P460, Hyper-Radiosensitivity Of Murine Scid Mutation, Complementing 1, DNA-PKC, DNAPKc, DNAPK, IMD26, XRCC7, P350, PRKDC, PRKDC, PRKDC , PRKDC , Protein Kinase, DNA-Activated, Catalytic Subunit, Protein Kinase, DNA-Activated, Catalytic Subunit, Protein Kinase, DNA-Activated, Catalytic Subunit , Protein Kinase, DNA-Activated, Catalytic Subunit , DNA-Dependent Protein Kinase Catalytic Subunit, DNA-Dependent Protein Kinase Catalytic Subunit, DNA-Dependent Protein Kinase Catalytic Subunit , DNA-Dependent Protein Kinase Catalytic Subunit , Protein Kinase, DNA-Activated, Catalytic Polypeptide, Protein Kinase, DNA-Activated, Catalytic Polypeptide, Protein Kinase, DNA-Activated, Catalytic Polypeptide , Protein Kinase, DNA-Activated, Catalytic Polypeptide , DNA-PK Ca |
Gene, Accession # | PRKDC, Gene ID: 5591, UniProt: P78527 |
Catalog # | abx032004 |
Price | please inquire |
Order / More Info | DNA-Dependent Protein Kinase Catalytic Subunit Phospho-Thr2609 (PRKDC pT2609) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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