Edit |   |
---|---|
Antigenic Specificity | NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. |
Immunogen | KLH-conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human NLRP3. |
Other Names | C1orf7, CIAS1, NALP3, PYPAF1, NACHT, LRR and PYD domains-containing protein 3, Angiotensin/vasopressin receptor AII/AVP-like, Caterpiller protein 1.1, CLR1.1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, PYRIN-containing APAF1-like protein 1, FCU, MWS, FCAS, Mmig1, AII/AVP, AGTAVPRL, Cold-induced autoinflammatory syndrome, NLRP3, Cold autoinflammatory syndrome 1 protein homolog, Mast cell maturation-associated-inducible protein 1, PYRI, C1orf7, C1orf7, C1orf7 , C1orf7 , CIAS1, CIAS1, CIAS1 , CIAS1 , NALP3, NALP3, NALP3 , NALP3 , PYPAF1, PYPAF1, PYPAF1 , PYPAF1 , NACHT, NACHT, NACHT , NACHT , LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3 , LRR and PYD domains-containing protein 3 , Angiotensin/vasopressin receptor AII/AVP-like, Angiotensin/vasopressin receptor AII/AVP-like, Angiotensin/vasopressin receptor AII/AVP-like , Angiotensin/vasopressin receptor AII/AVP-like , Caterpiller protein 1.1, |
Gene, Accession # | NLRP3, NCBI: NP_001073289.1, NP_001120933.1, NP_001120934.1, NP_001230062.1, NP_004886.3, NP_899632.1, UniProt: Q96P20 |
Catalog # | abx034000 |
Price | please inquire |
Order / More Info | NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950