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Antigenic Specificity | Adiponectin Receptor 1 (ADIPOR1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADIPOR1 antibody is a Rabbit polyclonal antibody against ADIPOR1. Adiponectin is a circulating hormone secreted by adipocytes that improves the metabolism of glucose and lipids, and is expressed at low levels in those with obesity and diabetes. Adiponectin receptors AdipoR1 and AdipoR2, also designated progestin and adipoQ receptor family members I and II, respectively, regulate fatty acid oxidation and the uptake of glucose by adiponectin. Each receptor activates a unique set of signaling molecules including AMPK, p38 MAPK and PPARa. AdipoR1 has a high-affinity for globular adiponectin and low-affinity for full-length adiponectin, while AdipoR2 has an intermediate affinity for both forms. AdipoR1 and AdipoR2 are mainly expressed in liver and muscle. Adiponectin, AdipoR1 and AdipoR2 are all associated with body composition, Insulin sensitivity, and metabolic parameters. Physical training increases circulating adiponectin and mRNA expression of AdipoR1 and AdipoR2 in muscle, which may mediate the improvement of Insulin resistance and the metabolic syndrome in response to exercise. |
Immunogen | Recombinant protein of human ADIPOR1. |
Other Names | Adiponectin receptor protein 1, Progestin and adipoQ receptor family member I, ADIPOR1, PAQR11, CGI-45, PAQR1, TESBP1A, Adiponectin receptor protein 1, Adiponectin receptor protein 1, Adiponectin receptor protein 1 , Adiponectin receptor protein 1 , Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member I , Progestin and adipoQ receptor family member I , ADIPOR1, ADIPOR1, ADIPOR1 , ADIPOR1 , PAQR11, PAQR11, PAQR11 , PAQR11 , CGI-45, CGI-45, CGI-45 , CGI-45 , PAQR1, PAQR1, PAQR1 , PAQR1 , TESBP1A, TESBP1A, TESBP1A , TESBP1A |
Gene, Accession # | ADIPOR1, Gene ID: 51094, UniProt: Q96A54 |
Catalog # | abx001271 |
Price | please inquire |
Order / More Info | Adiponectin Receptor 1 (ADIPOR1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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