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Antigenic Specificity | Splicing Factor, Arginine/serine-Rich 2 (SFRS2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5' and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5' and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway. |
Immunogen | KLH-conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human SFRS2. |
Other Names | SFRS2, SRSF2, Serine/arginine-rich splicing factor 2, Protein PR264, Splicing component, 35 kDa, Splicing factor SC35, Splicing factor, arginine/serine-rich 2, SFRS2, SFRS2, SFRS2 , SFRS2 , SRSF2, SRSF2, SRSF2 , SRSF2 , Serine/arginine-rich splicing factor 2, Serine/arginine-rich splicing factor 2, Serine/arginine-rich splicing factor 2 , Serine/arginine-rich splicing factor 2 , Protein PR264, Protein PR264, Protein PR264 , Protein PR264 , Splicing component, Splicing component, Splicing component , Splicing component , 35 kDa, 35 kDa, 35 kDa , 35 kDa , Splicing factor SC35, Splicing factor SC35, Splicing factor SC35 , Splicing factor SC35 , Splicing factor, Splicing factor, Splicing factor , Splicing factor , arginine/serine-rich 2, arginine/serine-rich 2, arginine/serine-rich 2 , arginine/serine-rich 2 |
Gene, Accession # | UniProt: Q01130 |
Catalog # | abx031712 |
Price | please inquire |
Order / More Info | Splicing Factor, Arginine/serine-Rich 2 (SFRS2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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