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Antigenic Specificity | Toll-Like Receptor 6 (TLR6) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse TLR6. |
Other Names | Tlr2, Toll-like receptor 2, CD282, Tlr2, Tlr2, Tlr2 , Tlr2 , Toll-like receptor 2, Toll-like receptor 2, Toll-like receptor 2 , Toll-like receptor 2 , CD282, CD282, CD282 , CD282 |
Gene, Accession # | UniProt: Q9EPW9 |
Catalog # | abx028484 |
Price | please inquire |
Order / More Info | Toll-Like Receptor 6 (TLR6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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