STEAP3 Metalloreductase (STEAP3) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-STEAP3 Metalloreductase (STEAP3) antibody, protein, ELISA kits.
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| Antigenic Specificity | STEAP3 Metalloreductase (STEAP3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | STEAP3 antibody is a Rabbit polyclonal antibody against STEAP3. Caspases modulate apoptosis in various ways. Specifically, Caspase-3, a death protease, is instrumental in cleaving cellular proteins, dismantling the cell and forming apoptotic bodies. pHyde has a potential role as a tumor suppressor by inducing caspase-3-mediated apoptosis and stimulating p53 expression. A dose-dependent increase in caspase-3 activity is observed in transduced pHyde DU145 cells. Furthermore, caspase-3 may be necessary for pHyde-mediated apoptosis. The pHyde gene may upregulate the apoptosis pathway and thus have a potential application in cancer gene therapy. Recombinant pHyde inhibits the growth of human prostate cancer cell lines DU145 and LNCaP in vitro. DU145 tumors may be reduced significantly in vivo when nude mice are injected with recombinant pHyde. pHyde also has a demonstrated growth inhibitory effect on human breast cancer cells. This suggests that pHyde may have a role in inhibiting different tumor types. |
| Immunogen | Recombinant protein of human STEAP3. |
| Other Names | Metalloreductase STEAP3, STEAP3, TSAP6, Dudulin-2, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, hTSAP6, pHyde, hpHyde, STMP3, dudlin-2, Metalloreductase STEAP3, Metalloreductase STEAP3, Metalloreductase STEAP3 , Metalloreductase STEAP3 , STEAP3, STEAP3, STEAP3 , STEAP3 , TSAP6, TSAP6, TSAP6 , TSAP6 , Dudulin-2, Dudulin-2, Dudulin-2 , Dudulin-2 , Six-transmembrane epithelial antigen of prostate 3, Six-transmembrane epithelial antigen of prostate 3, Six-transmembrane epithelial antigen of prostate 3 , Six-transmembrane epithelial antigen of prostate 3 , Tumor suppressor-activated pathway protein 6, Tumor suppressor-activated pathway protein 6, Tumor suppressor-activated pathway protein 6 , Tumor suppressor-activated pathway protein 6 , hTSAP6, hTSAP6, hTSAP6 , hTSAP6 , pHyde, pHyde, pHyde , pHyde , hpHyde, hpHyde, hpHyde , hpHyde , STMP3, STMP3, STMP3 , STMP3 , dudlin-2, dudlin-2, dudlin-2 , dudlin-2 |
| Gene, Accession # | STEAP3, Gene ID: 55240, UniProt: Q658P3 |
| Catalog # | abx000818 |
| Price | please inquire |
| Order / More Info | STEAP3 Metalloreductase (STEAP3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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