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Antigenic Specificity | Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | 1.25 mg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIRAP antibody is a Rabbit polyclonal antibody against TIRAP. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP. |
Other Names | MAL, Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, wyatt, BACTS1, TIRAP, Adapter protein wyatt, toll-interleukin 1 receptor (TIR) domain containing adaptor protein, HGNC:17192, FLJ42305, Toll-interleukin 1 receptor (TIR) domain-containing adapter protein, Toll-inte, MAL, MAL, MAL , MAL , Toll/interleukin-1 receptor domain-containing adapter protein, Toll/interleukin-1 receptor domain-containing adapter protein, Toll/interleukin-1 receptor domain-containing adapter protein , Toll/interleukin-1 receptor domain-containing adapter protein , TIR domain-containing adapter protein, TIR domain-containing adapter protein, TIR domain-containing adapter protein , TIR domain-containing adapter protein , Adaptor protein Wyatt, Adaptor protein Wyatt, Adaptor protein Wyatt , Adaptor protein Wyatt , MyD88 adapter-like protein, MyD88 adapter-like protein, MyD88 adapter-like protein , |
Gene, Accession # | TIRAP, Gene ID: 114609, NCBI: NP_001034750.1, UniProt: P58753-1 |
Catalog # | abx001586 |
Price | please inquire |
Order / More Info | Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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