Jumonji Domain-Containing Protein 4 (JMJD4) Antibody from ABBEXA LTD

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Antigenic SpecificityJumonji Domain-Containing Protein 4 (JMJD4)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionCovalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe (II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human JMJD4.
Other NamesJmjC domain-containing protein 4, Jumonji domain-containing protein 4, JMJD4, JmjC domain-containing protein 4, JmjC domain-containing protein 4, JmjC domain-containing protein 4 , JmjC domain-containing protein 4 , Jumonji domain-containing protein 4, Jumonji domain-containing protein 4, Jumonji domain-containing protein 4 , Jumonji domain-containing protein 4 , JMJD4, JMJD4, JMJD4 , JMJD4
Gene, Accession #UniProt: Q9H9V9
Catalog #abx025007
Priceplease inquire
Order / More InfoJumonji Domain-Containing Protein 4 (JMJD4) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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