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Antigenic Specificity | Jumonji/ARID Domain-Containing Protein 1B (JARID1B) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. |
Immunogen | KLH-conjugated synthetic peptide between 192-224 amino acids from the N-terminal region of human JARID1B. |
Other Names | KDM5B, JARID1B, PLU1, RBBP2H1, Lysine-specific demethylase 5B, Cancer/testis antigen 31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, KDM5B, KDM5B, KDM5B , KDM5B , JARID1B, JARID1B, JARID1B , JARID1B , PLU1, PLU1, PLU1 , PLU1 , RBBP2H1, RBBP2H1, RBBP2H1 , RBBP2H1 , Lysine-specific demethylase 5B, Lysine-specific demethylase 5B, Lysine-specific demethylase 5B , Lysine-specific demethylase 5B , Cancer/testis antigen 31, Cancer/testis antigen 31, Cancer/testis antigen 31 , Cancer/testis antigen 31 , Histone demethylase JARID1B, Histone demethylase JARID1B, Histone demethylase JARID1B , Histone demethylase JARID1B , Jumonji/ARID domain-containing protein 1B, Jumonji/ARID domain-containing protein 1B, Jumonji/ARID domain-containing protein 1B , Jumonji/ARID domain-containing protein 1B , PLU-1, PLU-1, PLU-1 , PLU-1 , Retinoblastoma-binding protein 2 homolog 1, Retinoblastoma-binding protein 2 homolog 1, |
Gene, Accession # | KDM5B, UniProt: Q9UGL1 |
Catalog # | abx028081 |
Price | please inquire |
Order / More Info | Jumonji/ARID Domain-Containing Protein 1B (JARID1B) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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