Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) antibody, protein, ELISA kits.
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| Antigenic Specificity | Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | 1.33 mg/ml |
| Applications | WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TNFSF10 Antibody is a Rabbit Polyclonal antibody against TNFSF10. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to 39-250 AA of human TNFSF10. |
| Other Names | Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL, TL2, Tumor Necrosis Factor Ligand Superfamily Member 10 Protein, Apo-2 ligand, Apo-2 ligand, Apo-2 ligand, Apo-2 ligand, Apo-2L, Apo-2L, Apo-2L, Apo-2L, TNF-related apoptosis-inducing ligand, TNF-related apoptosis-inducing ligand, TNF-related apoptosis-inducing ligand, TNF-related apoptosis-inducing ligand, Protein TRAIL, Protein TRAIL, Protein TRAIL, Protein TRAIL, CD253, CD253, CD253, CD253, TNFSF10, TNFSF10, TNFSF10, TNFSF10, APO2L, APO2L, APO2L, APO2L, TRAIL, TRAIL, TRAIL, TRAIL, TL2, TL2, TL2, TL2, Tumor Necrosis Factor Ligand Superfamily Member 10 Protein, Tumor Necrosis Factor Ligand Superfamily Member 10 Protein, Tumor Necrosis Factor Ligand Superfamily Member 10 Protein, Tumor Necrosis Factor Ligand Superfamily Member 10 Protein |
| Gene, Accession # | TNFSF10, Gene ID: 8743, UniProt: P50591 |
| Catalog # | abx001750 |
| Price | please inquire |
| Order / More Info | Tumor Necrosis Factor Ligand Superfamily Member 10 / TRAIL (TNFSF10) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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