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Antigenic Specificity | Protein Tyrosine Phosphatase, Non-Receptor Type 6 (PTPN6) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTPN6 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. |
Immunogen | KLH-conjugated synthetic peptide between 247-277 amino acids from the Central region of human PTPN6. |
Other Names | Hematopoietic Cell Protein-Tyrosine Phosphatase, Protein-Tyrosine Phosphatase 1C, Ptp-1C, Protein-Tyrosine Phosphatase Shp-1, Sh-Ptp1, Ptpn6, Hcp, Ptp1C, HCPH, HPTP1C, SHP-1, SHP-1L, SHP1, Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic Cell Protein-Tyrosine Phosphatase, Hematopoietic Cell Protein-Tyrosine Phosphatase, Hematopoietic Cell Protein-Tyrosine Phosphatase , Hematopoietic Cell Protein-Tyrosine Phosphatase , Protein-Tyrosine Phosphatase 1C, Protein-Tyrosine Phosphatase 1C, Protein-Tyrosine Phosphatase 1C , Protein-Tyrosine Phosphatase 1C , Ptp-1C, Ptp-1C, Ptp-1C , Ptp-1C , Protein-Tyrosine Phosphatase Shp-1, Protein-Tyrosine Phosphatase Shp-1, Protein-Tyrosine Phosphatase Shp-1 , Protein-Tyrosine Phosphatase Shp-1 , Sh-Ptp1, Sh-Ptp1, Sh-Ptp1 , Sh-Ptp1 , Ptpn6, Ptpn6, Ptpn6 , Ptpn6 , Hcp, Hcp, Hcp , Hcp , Ptp1C, Ptp1C, Ptp1C , Ptp1C , HCPH, HCPH, HCPH , HCPH , HPTP1C, HPTP1C, HPTP1C , HPTP1C , SHP-1, SHP-1, SHP-1 , SHP-1 , SHP-1L, SHP-1L, SHP-1L , SH |
Gene, Accession # | UniProt: P29350 |
Catalog # | abx031724 |
Price | please inquire |
Order / More Info | Protein Tyrosine Phosphatase, Non-Receptor Type 6 (PTPN6) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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