Edit |   |
---|---|
Antigenic Specificity | Lysine-Specific Demethylase 3A (KDM3A) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and a-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis. |
Immunogen | Purified recombinant fragment of human KDM3A expressed in E. Coli. |
Other Names | DKFZp686A24246, DKFZp686P07111, JHDM2A, JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA, KDM3A, DKFZp686A24246, DKFZp686A24246, DKFZp686A24246 , DKFZp686A24246 , DKFZp686P07111, DKFZp686P07111, DKFZp686P07111 , DKFZp686P07111 , JHDM2A, JHDM2A, JHDM2A , JHDM2A , JHMD2A, JHMD2A, JHMD2A , JHMD2A , JMJD1, JMJD1, JMJD1 , JMJD1 , JMJD1A, JMJD1A, JMJD1A , JMJD1A , KIAA0742, KIAA0742, KIAA0742 , KIAA0742 , TSGA, TSGA, TSGA , TSGA , KDM3A, KDM3A, KDM3A , KDM3A |
Gene, Accession # | KDM3A, Gene ID: 55818, UniProt: Q9Y4C1 |
Catalog # | abx012111 |
Price | please inquire |
Order / More Info | Lysine-Specific Demethylase 3A (KDM3A) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950