Cellular Tumor Antigen P53 (TP53) Antibody from ABBEXA LTD
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| Antigenic Specificity | Cellular Tumor Antigen P53 (TP53) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TP53. |
| Other Names | bbl, bfy, bhy, p44, p53, Tp53, BCC7, LFS1, TRP53, FLJ92943, Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, bbl, bbl, bbl , bbl , bfy, bfy, bfy , bfy , bhy, bhy, bhy , bhy , p44, p44, p44 , p44 , p53, p53, p53 , p53 , Tp53, Tp53, Tp53 , Tp53 , BCC7, BCC7, BCC7 , BCC7 , LFS1, LFS1, LFS1 , LFS1 , TRP53, TRP53, TRP53 , TRP53 , FLJ92943, FLJ92943, FLJ92943 , FLJ92943 , Cellular tumor antigen p53, Cellular tumor antigen p53, Cellular tumor antigen p53 , Cellular tumor antigen p53 , Antigen NY-CO-13, Antigen NY-CO-13, Antigen NY-CO-13 , Antigen NY-CO-13 , Phosphoprotein p53, Phosphoprotein p53, Phosphoprotein p53 , Phosphoprotein p53 , Tumor suppressor p53, Tumor suppressor p53, Tumor suppressor p53 , Tumor suppressor p53 |
| Gene, Accession # | UniProt: P04637 |
| Catalog # | abx034682 |
| Price | please inquire |
| Order / More Info | Cellular Tumor Antigen P53 (TP53) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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