Synapses of Amphids Defective Homolog 1 (SAD1) Antibody from ABBEXA LTD
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| Antigenic Specificity | Synapses of Amphids Defective Homolog 1 (SAD1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV or methyl methane sulfonate (MMS) induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regulator. The BRSK1 transcript is expressed ubiquitously with the highest levels of expression in brain and testis. |
| Immunogen | KLH-conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human SAD1 (BRSK1). |
| Other Names | BRSK1, KIAA1811, SAD1, SADB, Serine/threonine-protein kinase BRSK1, Brain-selective kinase 1, Brain-specific serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Synapses of Amphids Defective homolog 1, BRSK1, BRSK1, BRSK1 , BRSK1 , KIAA1811, KIAA1811, KIAA1811 , KIAA1811 , SAD1, SAD1, SAD1 , SAD1 , SADB, SADB, SADB , SADB , Serine/threonine-protein kinase BRSK1, Serine/threonine-protein kinase BRSK1, Serine/threonine-protein kinase BRSK1 , Serine/threonine-protein kinase BRSK1 , Brain-selective kinase 1, Brain-selective kinase 1, Brain-selective kinase 1 , Brain-selective kinase 1 , Brain-specific serine/threonine-protein kinase 1, Brain-specific serine/threonine-protein kinase 1, Brain-specific serine/threonine-protein kinase 1 , Brain-specific serine/threonine-protein kinase 1 , Serine/threonine-protein kinase SAD-B, Serine/threonine-protein kinase SAD-B, Serine/threonine-protein kinase SAD-B , Serine/threonine-protein kinase SAD-B , Synapses of Amphids |
| Gene, Accession # | UniProt: Q8TDC3 |
| Catalog # | abx033926 |
| Price | please inquire |
| Order / More Info | Synapses of Amphids Defective Homolog 1 (SAD1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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