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Antigenic Specificity | Mouse Ptk2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly (By similarity). Plays a potential role in oncogenic transformations resulting in increased kinase activity. |
Immunogen | KLH-conjugated synthetic peptide between 426-453 amino acids from the Central region of mouse Ptk2. |
Other Names | Ptk2, Fadk, Fak, Fak1, Kiaa4203, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, Protein-tyrosine kinase 2, p125FAK, pp125FAK, Ptk2, Ptk2 , Ptk2 , Ptk2, Fadk, Fadk , Fadk , Fadk, Fak, Fak , Fak , Fak, Fak1, Fak1 , Fak1 , Fak1, Kiaa4203, Kiaa4203 , Kiaa4203 , Kiaa4203, Focal adhesion kinase 1, Focal adhesion kinase 1 , Focal adhesion kinase 1 , Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, Focal adhesion kinase-related nonkinase , Focal adhesion kinase-related nonkinase , Focal adhesion kinase-related nonkinase, Protein-tyrosine kinase 2, Protein-tyrosine kinase 2 , Protein-tyrosine kinase 2 , Protein-tyrosine kinase 2, p125FAK, p125FAK , p125FAK , p125FAK, pp125FAK, pp125FAK , pp125FAK , pp125FAK |
Gene, Accession # | UniProt: P34152 |
Catalog # | abx028067 |
Price | please inquire |
Order / More Info | Mouse Ptk2 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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