DANRE park7 Antibody from ABBEXA LTD

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Antigenic SpecificityDANRE park7
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesZebrafish
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionProtects cells against oxidative stress and cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone (By similarity). Protects dopaminergic neurons against cell death arising from oxidative stress and proteasome inhibition, probably by a TP53/p53-dependent mechanism.
ImmunogenKLH-conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of DANRE park7.
Other Namespark7, dj1, Protein DJ-1, Parkinson disease protein 7 homolog, park7, park7, park7 , park7 , dj1, dj1, dj1 , dj1 , Protein DJ-1, Protein DJ-1, Protein DJ-1 , Protein DJ-1 , Parkinson disease protein 7 homolog, Parkinson disease protein 7 homolog, Parkinson disease protein 7 homolog , Parkinson disease protein 7 homolog
Gene, Accession #NCBI: NP_001005938.1, UniProt: Q5XJ36
Catalog #abx034927
Priceplease inquire
Order / More InfoDANRE park7 Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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