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Antigenic Specificity | DANRE park7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Zebrafish |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protects cells against oxidative stress and cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone (By similarity). Protects dopaminergic neurons against cell death arising from oxidative stress and proteasome inhibition, probably by a TP53/p53-dependent mechanism. |
Immunogen | KLH-conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of DANRE park7. |
Other Names | park7, dj1, Protein DJ-1, Parkinson disease protein 7 homolog, park7, park7, park7 , park7 , dj1, dj1, dj1 , dj1 , Protein DJ-1, Protein DJ-1, Protein DJ-1 , Protein DJ-1 , Parkinson disease protein 7 homolog, Parkinson disease protein 7 homolog, Parkinson disease protein 7 homolog , Parkinson disease protein 7 homolog |
Gene, Accession # | NCBI: NP_001005938.1, UniProt: Q5XJ36 |
Catalog # | abx034927 |
Price | please inquire |
Order / More Info | DANRE park7 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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