NKG2D Ligand 2 (ULBP2) Antibody from ABBEXA LTD
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| Antigenic Specificity | NKG2D Ligand 2 (ULBP2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. |
| Immunogen | KLH-conjugated synthetic peptide between 88-116 amino acids from the Central region of human ULBP2. |
| Other Names | N2DL2, RAET1H, NKG2D ligand 2, N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, N2DL2, N2DL2, N2DL2 , N2DL2 , RAET1H, RAET1H, RAET1H , RAET1H , NKG2D ligand 2, NKG2D ligand 2, NKG2D ligand 2 , NKG2D ligand 2 , N2DL-2, N2DL-2, N2DL-2 , N2DL-2 , NKG2DL2, NKG2DL2, NKG2DL2 , NKG2DL2 , ALCAN-alpha, ALCAN-alpha, ALCAN-alpha , ALCAN-alpha , Retinoic acid early transcript 1H, Retinoic acid early transcript 1H, Retinoic acid early transcript 1H , Retinoic acid early transcript 1H , UL16-binding protein 2, UL16-binding protein 2, UL16-binding protein 2 , UL16-binding protein 2 |
| Gene, Accession # | ULBP2, UniProt: Q9BZM5 |
| Catalog # | abx029272 |
| Price | please inquire |
| Order / More Info | NKG2D Ligand 2 (ULBP2) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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