Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody from ABBEXA LTD
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| Antigenic Specificity | Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | ascites |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. beta arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Immunogen | Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli. |
| Other Names | MAPK10, Mitogen-Activated Protein Kinase 10, Stress-Activated Protein Kinase JNK3, Stress-Activated Protein Kinase 1b, C-Jun N-Terminal Kinase 3, MAP Kinase P49 3F12, MAP Kinase 10, EC 2.7.11.24, PRKM10, SAPK1b, JNK3A, JNK3, Stress Activated Protein Kinase Beta, JNK3 Alpha Protein Kinase, EC 2.7.11, P54bSAPK, P493F12, MAPK 10, MAPK10/JNK3, JNK3/MAPK10, JNK-3, JNK 3, MAPK10, MAPK10, MAPK10 , MAPK10 , Mitogen-Activated Protein Kinase 10, Mitogen-Activated Protein Kinase 10, Mitogen-Activated Protein Kinase 10 , Mitogen-Activated Protein Kinase 10 , Stress-Activated Protein Kinase JNK3, Stress-Activated Protein Kinase JNK3, Stress-Activated Protein Kinase JNK3 , Stress-Activated Protein Kinase JNK3 , Stress-Activated Protein Kinase 1b, Stress-Activated Protein Kinase 1b, Stress-Activated Protein Kinase 1b , Stress-Activated Protein Kinase 1b , C-Jun N-Terminal Kinase 3, C-Jun N-Terminal Kinase 3, C-Jun N-Terminal Kinase 3 , C-Jun N-Terminal Kinase 3 , MAP Kinase P49 3F12, MAP Kinase |
| Gene, Accession # | Gene ID: 5602, UniProt: P53779 |
| Catalog # | abx011782 |
| Price | please inquire |
| Order / More Info | Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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