F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody from ABBEXA LTD

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Antigenic SpecificityF-Box/WD Repeat-Containing Protein 1A (BTRC)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB, IHC, IF/ICC
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DescriptionThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. It also associates specifically with phosphorylated IkappaBalpha and beta-catenin destruction motifs, probably functioning in multiple transcriptional programs by activating the NF-kappaB pathway and inhibiting the beta-catenin pathway.
ImmunogenKLH-conjugated synthetic peptide between 17-52 amino acids from the N-terminal region of human BTRC.
Other NamesBETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, MGC4643, bTrCP, bTrCP1, betaTrCP, BTRC, F-box/WD repeat-containing protein 1A, E3RSIkappaB, Epididymis tissue protein Li 2a, F-box and WD repeats protein beta-TrCP, pIkappaBalpha-E3 receptor subunit, pIkappaBalpha-E3 receptor subuni, BETA-TRCP, BETA-TRCP, BETA-TRCP , BETA-TRCP , FBW1A, FBW1A, FBW1A , FBW1A , FBXW1, FBXW1, FBXW1 , FBXW1 , FBXW1A, FBXW1A, FBXW1A , FBXW1A , FWD1, FWD1, FWD1 , FWD1 , MGC4643, MGC4643, MGC4643 , MGC4643 , bTrCP, bTrCP, bTrCP , bTrCP , bTrCP1, bTrCP1, bTrCP1 , bTrCP1 , betaTrCP, betaTrCP, betaTrCP , betaTrCP , BTRC, BTRC, BTRC , BTRC , F-box/WD repeat-containing protein 1A, F-box/WD repeat-containing protein 1A, F-box/WD repeat-containing protein 1A , F-box/WD repeat-containing protein 1A , E3RSIkappaB, E3RSIkappaB, E3RSIkappaB , E3RSIkappaB , Epididymis tissue protein Li 2a, Epididymis tissue protein Li 2a, Epididymis tissue protein Li 2a , Epididymis tissue protein Li 2a , F-box and WD repeats protein bet
Gene, Accession #BTRC, UniProt: Q9Y297
Catalog #abx026481
Priceplease inquire
Order / More InfoF-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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