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Antigenic Specificity | G Protein Pathway Suppressor 2 (GPS2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GPS2 antibody is a Rabbit polyclonal antibody against GPS2. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. |
Immunogen | Recombinant protein of human GPS2. |
Other Names | AMF-1, G protein pathway suppressor 2, Protein GPS2, GPS2, AMF-1, AMF-1, AMF-1 , AMF-1 , G protein pathway suppressor 2, G protein pathway suppressor 2, G protein pathway suppressor 2 , G protein pathway suppressor 2 , Protein GPS2, Protein GPS2, Protein GPS2 , Protein GPS2 , GPS2, GPS2, GPS2 , GPS2 |
Gene, Accession # | GPS2, Gene ID: 2874, UniProt: Q13227 |
Catalog # | abx002842 |
Price | please inquire |
Order / More Info | G Protein Pathway Suppressor 2 (GPS2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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