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Antigenic Specificity | EPH Receptor A2 (EphA2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, hamster |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families). |
Immunogen | KLH-conjugated synthetic peptide between 919-950 amino acids from the C-terminal region of human EphA2. |
Other Names | ECK, EPHA2, Ephrin type-A receptor 2 precursor, Epithelial cell kinase, kinase EphA2, MPK-5, SEK-2, SEK2, Tyrosine-protein kinase receptor ECK, Ephrin type-A receptor 2, EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, Human embryo kinase, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, Eph-like tyrosine kinase 1, EPHA4, HEK8, SEK, TYRO1, Ephrin type-A receptor 4, EPH-like kinase 8, EK8, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK, ECK, ECK, ECK , ECK , EPHA2, EPHA2, EPHA2 , EPHA2 , Ephrin type-A receptor 2 precursor, Ephrin type-A receptor 2 precursor, Ephrin type-A receptor 2 precursor , Ephrin type-A receptor 2 precursor , Epithelial cell kinase, Epithelial cell kinase, Epithelial cell kinase , Epithelial cell kinase , kinase EphA2, kinase EphA2, kinase EphA2 , kinase EphA2 , MPK-5, MPK-5, MPK-5 , MPK-5 , SEK-2, SEK-2, SEK-2 , SEK-2 , SEK2, SEK2, SEK2 , SEK2 , Tyrosine-protein kinase receptor |
Gene, Accession # | UniProt: P29317 |
Catalog # | abx033513 |
Price | please inquire |
Order / More Info | EPH Receptor A2 (EphA2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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