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Antigenic Specificity | KDR (pY1175) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl, |
Concentration | 1.72 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KDR (pY1175) antibody is a Rabbit polyclonal antibody against KDR (pY1175). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1175 of human KDR. |
Other Names | FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor, protein-tyrosine kinase receptor Flk-1, vascular endothelial growth factor receptor 2, kinase insert domain receptor (a type III receptor tyrosine kinase), CD309, VEGFR, VEGFR2, Vegfr-2, Fetal Liver Kinase 1, Flk-1, FLK1, FLK1, FLK1 , FLK1 , KDR, KDR, KDR , KDR , VGFR2, VGFR2, VGFR2 , VGFR2 , VGR2, VGR2, VGR2 , VGR2 , kinase insert domain receptor, kinase insert domain receptor, kinase insert domain receptor , kinase insert domain receptor , protein-tyrosine kinase receptor Flk-1, protein-tyrosine kinase receptor Flk-1, protein-tyrosine kinase receptor Flk-1 , protein-tyrosine kinase receptor Flk-1 , vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 2 , vascular endothelial growth factor receptor 2 , kinase insert domain receptor (a type III receptor tyrosine kinase), kinase insert domain receptor (a type III receptor tyrosine kinase), k |
Gene, Accession # | KDR, Gene ID: 3791, UniProt: P35968 |
Catalog # | abx000430 |
Price | please inquire |
Order / More Info | KDR (pY1175) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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